Feline Hyperthyroidism Protocols

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Our Veterinarian manages the 131I treatment program and provides all veterinary care during the cats’ stay at our facility. All cats must be assessed for adequate renal function prior to treatment. Blood-work/urinalysis provided should not be older then 6 weeks. Our Veterinarian will be involved in reviewing all documents provided by the referring veterinarian. Prior to the cats arrival our Veterinarian or Jane Sykes will contact the referring veterinarian if they have any concerns or questions. It will be left to the discretion of our Veterinarian if the cat is a suitable candidate for the 131I treatment. If possible the treatment with methimazole (Tapazole) should be terminated 2 weeks prior to radioiodine treatment. Note that it is estimated that approximately 2.5% of patients may develop hypothyroidism and will require treatment.

Standard
The expected range of the therapeutic dose for cats with a T4 greater then 125mmol/L is 2.0mCi – 6.0mCi. The therapeutic dose will be administered through subcutaneous injections. Following the therapeutic radioiodine dose the cats will be housed in the same room, however, in individual cages. Each cat will have a chance to exercise throughout the day. The activity in the excreta will be monitored and removed daily for each cat. Animal care will be provided six times throughout the day by AHT/VTs to ensure the animals are fed and watered sufficiently and for much needed TLC. All rooms for housing and waste storage meet the requirements of the Canadian Council of Animal Care (CCAC). All cats will stay approximately 8 days; and the dose rate at 30 cm from the cat’s thyroid does not exceed 10uSv/h or 1mR/hr.Litter must be kept for 14 days following treatment.Follow up T4 evaluation will be requested in approximately 9-10 months at the owner’s expense. The BUN and creatinine levels could also be checked at this time to re-evaluate kidney function.

Low Dose
The expected range of the therapeutic dose for cats with a T4 less then 90mmol/L is 0.4mCi – 0.6mCi. The therapeutic dose will be administered through subcutaneous injections. Follow up T4 evaluation will be requested in approximately 2-3 months at our expense. (continued)

Please fax or mail invoice directly to the office of Jane Sykes for payment. The BUN and creatinine levels could also be checked at this time to re-evaluate kidney function.

Reduced Kidney Function
The therapeutic dose for cats with decreased kidney function or cats that are suspected of having decreased kidney function following treatment will be evaluated as a standard injection. The dose will be divided into two separate injections, which will be separated by three months. Our goal is too allow the kidneys some time to adjust to the changes occurring. Following the therapeutic radioiodine dose the cats will be housed in the same room, however, in individual cages. Each cat will have a chance to exercise throughout the day. The activity in the excreta will be monitored and removed daily for each cat. Animal care will be provided six times throughout the day by AHT/VTs to ensure the animals are fed and watered sufficiently and for much needed TLC. All rooms for housing and waste storage meet the requirements of the Canadian Council of Animal Care (CCAC). Length of stay is Saturday to Wednesday for most cats; and the dose rate at 30 cm from the cat’s thyroid does not exceed 10uSv/h or 1mR/hr. Litter must be kept for one month following treatment. Prior to the second injection the T4 and kidney function must be re-evaluated. Please fax or mail the invoice directly to the office of Jane Sykes for payment.

Malignant
The expected range of the therapeutic dose for cats with a carcinoma is 10.0mCi – 14.0mCi. The therapeutic dose will be administered through two subcutaneous injections. Following the therapeutic radioiodine dose the cats will be housed in the same room, however, in individual cages. Each cat will have a chance to exercise throughout the day. The activity in the excreta will be monitored and removed daily for each cat. Animal care will be provided six times throughout the day by AHT/VTs to ensure the animals are fed and watered sufficiently and for much needed TLC. All rooms for housing and waste storage meet the requirements of the Canadian Council of Animal Care (CCAC). All cats will stay approximately 21 days; and the dose rate at 30 cm from the cat’s thyroid does not exceed 10uSv/h or 1mR/hr. Litter must be kept for one month following treatment. Follow up T4 evaluation will be requested in approximately 9-10 months at the owner’s expense. The BUN and creatinine levels could also be checked at this time to re-evaluate kidney function.


Feline Hyperthyroidism
 
Thames Valley Veterinary Services
London, Ontario
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